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[4] [6] The direct delivery of ascorbic acid into the bloodstream allows for supraphysiological concentrations, which could have distinct biological effects, such as pro-oxidant activity in the presence of transition metals or selective cytotoxicity against certain malignant cells, although these applications remain under investigation and are not universally accepted as standard of care

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The observed effects in this study were also observed with physical phenotype, as frail women who were born to lean and normal-weight mothers conferred greater RT-related white matter benefits compared to those born to obese mothers