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GLP-1 receptor agonists—the class of drugs that includes semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)—are synthetic molecules engineered to mimic and amplify this exact hormonal signal

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Investigators randomized 1,131 participants in a 2:1 ratio, with 754 receiving tolebrutinib and 377 receiving a matching placebo