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In order to observe the effect of XYP on ferroptosis, NCM460 cells were separated into five groups: control group, model group (RSL3, 15 μM) ( 2.12 Cell transfection NCM460 cells at around 40%–50% confluence were transfected with Nrf2 siRNA or negative control siRNA using riboFECT™ CP Transfection Kit according to the manufacturer’s instructions